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Rev. méd. Chile ; 145(10): 1342-1348, oct. 2017. graf
Article in Spanish | LILACS | ID: biblio-902449

ABSTRACT

Primary colorectal lymphoma is a rare form of presentation of gastrointestinal tract lymphomas. Inflammatory bowel disease and its treatment are risk factors for its development. We report a 47-year-old male patient with Ulcerative Colitis of two years of evolution, treated initially with azathioprine and later on with infliximab. Due to a relapse in symptoms after the second dose of infliximab, a new coloncoscopy was performed showing a rectal ulcerative lesion, corresponding to a large cell Non-Hodgkin's Lymphoma. The patient was successfully treated with RCHOP chemotherapy (Rituximab cyclophosphamide doxorubicin vincristine prednisone). He is currently in disease remission.


Subject(s)
Humans , Male , Middle Aged , Rectal Neoplasms/etiology , Rectal Neoplasms/pathology , Colitis, Ulcerative/drug therapy , Lymphoma, Large B-Cell, Diffuse/etiology , Lymphoma, Large B-Cell, Diffuse/pathology , Immunosuppressive Agents/adverse effects , Rectal Neoplasms/diagnostic imaging , Azathioprine/adverse effects , Vincristine/administration & dosage , Biopsy , Gastrointestinal Agents/adverse effects , Prednisone/administration & dosage , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Doxorubicin/administration & dosage , Lymphoma, Large B-Cell, Diffuse/diagnostic imaging , Cyclophosphamide/administration & dosage , Rituximab/administration & dosage , Infliximab/adverse effects , Positron Emission Tomography Computed Tomography
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